Mise en place. Pre-heat oven to 350°. Coat glass baking dish with non-stick spray (or grease with butter). Place fish in prepared dish. Dash with salt & pepper.
Heat oil in a large skillet over medium heat. Add pepper and onions. Cook 4 minutes. Add tomatoes and oregano. Cook 3 minutes. Stir in hot sauce.
Place vegetable mixture over prepared fish.
Bake at 350° for 25 minutes or until fish flakes easily. Serve with rice if desired. (Yellow best; brown and white also an option).